Finally, hypertension is a lifestyle-initiated disease induced by multiple causes, including poor diet, lack of physical activity, obesity and heightened stress (15).
The thousands of phytonutrients in plant-based foods, such as flavonoids, nitrates, and isoflavones, fulfill essential functions for cardiovascular health.
Thus, when evaluating any study, a full evaluation of the subjects’ dietary pattern is warranted to have a complete understanding of the dynamic interplay of nutrients on physiological factors. The role of high-fructose corn syrup in metabolic syndrome and hypertension.
Indeed, there are several points to consider when it comes to studies addressing dietary fructose and hypertension.
In this particular study by Angelopoulos et al., the subjects tested were healthy and had normal blood pressure. Le MT, Frye RF, Rivard CJ, Cheng J, Mc Fann KK, Segal MS, Johnson RJ, Johnson JA.
The fact that subjects were given milk may have been significant as dairy products contain naturally-occurring ACE-inhibitory peptides that can lower blood pressure (13).
Also, milk is high in a number of other nutrients have the potential to favorably alter blood pressure, such as potassium, calcium, magnesium, and vitamin D. The subjects in this study drank a sweetened milk beverage. It has been demonstrated that milk peptides can reduce blood pressure (13). The authors reported a significant reduction in both systolic and diastolic blood pressure with no change in uric acid levels despite an average two pound weight gain after the 10-week study. The results of this study might be surprising for some, considering there are studies available suggesting that fructose is associated with hypertension. Perez-Pozo SE, Schold J, Nakagawa T, Sánchez-Lozada LG, Johnson RJ, Lillo JL. Therefore, any detrimental effect of fructose (or other sweeteners or food constituents) might be negated or lessened in the context of healthy lifestyle patterns. Angelopoulos TJ, Lowndes J, Zukley L, Melanson KJ, Nguyen V, Huffman A, Rippe JM.